69M
people experience TBI globally1
80%
of TBIs are of mild severity2
*The NanoDx™ System has not been evaluated by the FDA or other regulatory agencies.
Limitations of Current Diagnostic Methods
Glasgow Coma Scale
- Subjective evaluation
- Inaccurate 56% of the time3
- Time-consuming
CT Scans
- More than 90% of CT scans performed are considered unnecessary4
- Only detects brain bleed 8% of the time5
- Costly and time-consuming
- Radiation up to 200 chest x-rays6
The NanoDx™ Tbit™ Test
The NanoDx™ System offers an objective alternative for assessing patients suspected of mild or moderate TBI at the point of care—quickly and cost-effectively*. Using our patented nano biosensor technology, the NanoDx™ Tbit™ test delivers accurate measurement of two biomarkers indicative of brain injury.
S100B
Calcium-binding peptide that increases from glial activation and/or death following TBI.7
GFAP
Glial fibrillary acidic protein is a type III intermediate filament protein that increases following TBI.8
Unique Combination of Benefits
Objective
Definitive assessment helps avoid misdiagnosed patients.
Fast
Accelerate clinical decisions with lab-accurate tests in 2 minutes.
Accurate
In a pre-clinical feasibility study (n=100) test demonstrated 100% sensitivity and 0 false negatives.
Easy
Delivers lab-accurate results with just a fingerstick of blood.
Learn More About the NanoDx™ System
References
- “Estimating the global incidence of traumatic brain injury,” Journ Neurosurg 2018.
- “Recommendations for Diagnosing a Mild Traumatic Brain Injury: A National Academy of Neuropsychology Education Paper,” Arch Clin Neuropsych 2009.
- “Accuracy of Mild Traumatic Brain Injury Diagnosis,” Arch Phys Med Rehabil 2008.
- “A prospective cluster-randomized trial to implement the Canadian CT Head Rule in emergency departments,” CMAJ 2010 Oct 5; 182(14): 1527–1532.
- Based on data from the “Emergency Department Evaluation of Traumatic Brain Injury in the U.S. 2009-2010,” J Head Trauma Rehabil 2016.
- “Radiation Dose Associated with Common CT Exams,” Arch Intern Med 2009.
- https://pubmed.ncbi.nlm.nih.gov/29716980
- https://ghr.nlm.nih.gov/gene/GFAP